Can you take probiotics with alcohol?

Probiotics are not medications and there are no specific contraindications which suggest that you can't take probiotics with alcohol. However, alcohol may harm delicate live cultures and populations of gut bacteria, so it is worth considering this if you're taking probiotic supplements.

We’re often asked, ‘Can I drink alcohol if I’m on probiotics supplements?’ As mentioned above, there aren’t any specific interactions between probiotics and alcohol. However, to fully answer that question, we need to explain a bit more about the effects of alcohol on the gut microbiome.

Image of drinks

Does alcohol kill gut bacteria?

There’s some evidence to suggest that drinking alcohol can kill good bacteria and have negative effects on the delicate balance of the gut microbiome 1,2. It is generally quite toxic to the body and places a strain on the body systems to process and excrete it. For more information about the effects of alcohol on the gut microbiome, read this article on the Probiotics Learning Lab about probiotics and hangovers.

So, if you are taking probiotics as part of your daily health regime, the odd alcoholic drink taken at a different time to your live cultures supplement should not be a problem. But if you’re regularly consuming large quantities of alcohol, then you’re probably not helping your gut health or getting the best value from your probiotic supplements!

How long after taking probiotics can I drink alcohol?

Knowing that alcohol is likely to negatively affect the gut bacteria and the delicate live cultures in our supplements, it makes sense not to take probiotics at the same time as an alcoholic drink. We recommend taking our supplements in the morning with breakfast, so we’d advise having any alcoholic beverages at least 4-6 hours later. This will give the friendly bacteria time to pass through the digestive system and begin to establish themselves in the gut. Read more about the best time to take probiotics.

Which are the best probiotics for alcohol drinkers?

Research is still in its infancy in this area, so there aren't yet any 'go-to' strains for alcohol drinkers; however there have been some encouraging results so far3. For now, if you know you're going to be having a few drinks, then it might be best to choose one of our higher strength supplements, such as Optibac Probiotics Every Day EXTRA. Taking a higher strength probiotic will introduce more friendly bacteria to the gut and this should help to complement the gut microbiome after a night on the town, but long-term, if you want to love your gut it's best to limit alcohol use and choose probiotic strains which have been researched for your individual health concerns. Read more about how different strains have different properties. 

Which alcoholic drink is best for gut bacteria?

Ideally, no alcohol is ‘best’ for the gut bacteria, as all alcoholic beverages will have some negative effects on the gut. However, there’s some research to suggest that compounds in red wine called polyphenols, which have antioxidant and anti-inflammatory properties, are also beneficial for gut health3. So if you want to consider your gut when choosing your tipple, you might be best to opt for a glass of red! For more information about this research, read Is Wine a Probiotic? over on the Probiotics Learning Lab.


To sum up, if you are following a health regime and are keen to try and complement and maintain your gut bacteria, then alcohol consumption is a consideration. The odd glass or two occasionally in the evening should not have a huge impact on your gut microbiome, especially if you choose alcoholic drinks like red wine, which can give your body some nutrients. But if you take your probiotics with alcohol, or regularly consume several units of alcohol each week, then this may affect your gut microbiome and your probiotics.

You may also be interested to read these other FAQs:

Can I take probiotics with my diet?

Can i take more than one Optibac probiotic?

This FAQ has been answered by Kerry Beeson BSc (Nut.Med). Nutritional Therapist



1. Engen PA, Green SJ, Voigt RM, Forsyth CB, Keshavarzian A. The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota. Alcohol Res. 2015;37(2):223-36. PMID: 26695747; PMCID: PMC4590619.
2. Wang SC, Chen YC, Chen SJ, Lee CH, Cheng CM. Alcohol Addiction, Gut Microbiota, and Alcoholism Treatment: A Review. Int J Mol Sci. 2020 Sep 3;21(17):6413. doi: 10.3390/ijms21176413. PMID: 32899236; PMCID: PMC7504034.
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